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== Article Draft ==
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'''Mercapturic acids''' are condensation products formed from the coupling of [[cysteine]] with [[aromatic compounds]].<ref name="thefreedictionary">[http://medical-dictionary.thefreedictionary.com/mercapturic+acid medical-dictionary.thefreedictionary.com] Retrieved on June 25, 2009</ref> They are formed as [[Conjugation (biochemistry)|conjugates]] in the liver and are excreted in the [[urine]].<ref name="thefreedictionary" />
[[Glutathione]] adducts lose [[glutamate]] and [[glycine]] portions, and are [[Acetylation|acetylated]] to form mercapturic acids, which are excreted.
Levels of mercapturic acids in urine may be used as an indicator of exposure to, e.g., [[ethylene dibromide]],<ref>{{cite journal |vauthors=Kim DH, Guengerich FP |date=November 1989 |title=Excretion of the mercapturic acid S-[2-(N7-guanyl)ethyl]-N-acetylcysteine in urine following administration of ethylene dibromide to rats |journal=Cancer Res. |volume=49 |issue=21 |pages=5843–7 |pmid=2790795}}</ref> [[acrylamide]], and [[terbuthylazine]].<ref>{{cite journal |vauthors=Mercadante R, Polledri E, Fustinoni S |date=July 2012 |title=Determination of terbuthylazine and desethylterbuthylazine in human urine and hair samples by eletrospray ionization-liquid chromatography/triple quadrupole mass spectrometry |journal=Analytical and Bioanalytical Chemistry |volume=404 |issue=3 |pages=875–86 |doi=10.1007/s00216-012-6184-3 |pmid=22752446 |s2cid=2087135}}</ref>
The name "'''mercapturic acid'''" is a combination of "mercapturic" and "acid". The latter indicates that the compound is an acid. The former is a [[Compound (linguistics)|compound word]] consisting of the [[Word stem|stem]] "mercaptur-", coming from "[[mercaptan]]", and the [[suffix]] "-ic", meaning "having the character of". In sum, the name "'''mercapturic acid"''' means "an acid with mercaptan character/nature".<ref>{{Cite web |date=2024-03-26 |title=Definition of IC |url=https://www.merriam-webster.com/dictionary/IC |access-date=2024-04-27 |website=www.merriam-webster.com |language=en}}</ref>
=== References ===
[[Category:Wikipedia Student Program]]
Okumaya devam et...
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{{Dashboard.wikiedu.org draft template/about this sandbox}}
== Article Draft ==
=== Lead ===
=== Article body ===
'''Mercapturic acids''' are condensation products formed from the coupling of [[cysteine]] with [[aromatic compounds]].<ref name="thefreedictionary">[http://medical-dictionary.thefreedictionary.com/mercapturic+acid medical-dictionary.thefreedictionary.com] Retrieved on June 25, 2009</ref> They are formed as [[Conjugation (biochemistry)|conjugates]] in the liver and are excreted in the [[urine]].<ref name="thefreedictionary" />
[[Glutathione]] adducts lose [[glutamate]] and [[glycine]] portions, and are [[Acetylation|acetylated]] to form mercapturic acids, which are excreted.
Levels of mercapturic acids in urine may be used as an indicator of exposure to, e.g., [[ethylene dibromide]],<ref>{{cite journal |vauthors=Kim DH, Guengerich FP |date=November 1989 |title=Excretion of the mercapturic acid S-[2-(N7-guanyl)ethyl]-N-acetylcysteine in urine following administration of ethylene dibromide to rats |journal=Cancer Res. |volume=49 |issue=21 |pages=5843–7 |pmid=2790795}}</ref> [[acrylamide]], and [[terbuthylazine]].<ref>{{cite journal |vauthors=Mercadante R, Polledri E, Fustinoni S |date=July 2012 |title=Determination of terbuthylazine and desethylterbuthylazine in human urine and hair samples by eletrospray ionization-liquid chromatography/triple quadrupole mass spectrometry |journal=Analytical and Bioanalytical Chemistry |volume=404 |issue=3 |pages=875–86 |doi=10.1007/s00216-012-6184-3 |pmid=22752446 |s2cid=2087135}}</ref>
The name "'''mercapturic acid'''" is a combination of "mercapturic" and "acid". The latter indicates that the compound is an acid. The former is a [[Compound (linguistics)|compound word]] consisting of the [[Word stem|stem]] "mercaptur-", coming from "[[mercaptan]]", and the [[suffix]] "-ic", meaning "having the character of". In sum, the name "'''mercapturic acid"''' means "an acid with mercaptan character/nature".<ref>{{Cite web |date=2024-03-26 |title=Definition of IC |url=https://www.merriam-webster.com/dictionary/IC |access-date=2024-04-27 |website=www.merriam-webster.com |language=en}}</ref>
=== References ===
[[Category:Wikipedia Student Program]]
Okumaya devam et...